Diabetes remission and relapse after metabolic surgery

Determinants of Diabetes Remission and Glycemic Control After Bariatric Surgery.

OBJECTIVE Eligibility criteria for bariatric surgery in diabetes include BMI ≥35 kg/m(2) and poorly controlled glycemia. However, BMI does not predict diabetes remission, and thus, predictors need to be identified. RESEARCH DESIGN AND METHODS Seven hundred twenty-seven patients were included in a database merged from the Swedish Obese Subjects (SOS) study and two randomized controlled studies...

Diabetes remission after bariatric surgery: which are the mechanisms?

Bariatric surgery is being performed increasingly in response to the epidemic of obesity plaguing the Western society. The numbers of such procedures have increased sharply worldwide, with the Roux-en-Y gastric bypass (GBP) currently being considered as the gold-standard operative treatment for morbid obesity. Its widespread acceptance lies in part in its remarkable success in reducing weight o...

Remission of type 2 diabetes after bariatric surgery.

Insulin cessation and diabetes remission after bariatric surgery in adults with insulin-treated type 2 diabetes.

OBJECTIVE The impact of bariatric surgeries on insulin-treated type 2 diabetes (I-T2D) in the general population is largely undocumented. We assessed changes in insulin treatment after bariatric surgery in a large cohort of I-T2D patients, comparing Roux-en-Y gastric bypass surgery (RYGB) with laparoscopic adjustable gastric banding (LAGB), controlling for differences in weight loss between pro...

Clinical Outcomes of Metabolic Surgery: Efficacy of Glycemic Control, Weight Loss, and Remission of Diabetes

Since the 2007 Diabetes Surgery Summit in Rome, Italy, and the subsequent publishing of the world's first guidelines for the surgical treatment of type 2 diabetes (T2D), much new evidence regarding the efficacy and safety of metabolic surgery has emerged. Additional observational cohort studies support the superior effects of surgery over medical treatment with respect to glycemic control, weig...